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Focal cortical dysplasia is a malformation of the cerebral cortex associated with one of the most severe types of epilepsy. Treatment is difficult owing to a lack of effective drugs or access to surgery. A new human model developed by researchers at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, using organoids cultured from patients’ cells has now opened up opportunities to test more specific therapies and medications. In partnership with a group at the [...]

A study conducted at São Paulo State University (UNESP) in Brazil shows that even mild to moderate infection by SARS-CoV-2 can cause an imbalance in the cardiovascular system of young adults without pre-existing diseases. The researchers also concluded that both obesity and a low level of physical activity are key factors in post-COVID that help alter the autonomic nervous system, which regulates such vital functions as blood pressure, heart rate and breathing. A study conducted at [...]

Several natural disasters have afflicted various parts of Brazil since 2022 began, from deadly flooding and mudslides due to abnormally heavy rain in the states of Minas Gerais, Bahia, Rio de Janeiro and São Paulo, to severe drought in Rio Grande do Sul state. However, only 6.1% of its 5,568 municipalities have plans of any kind to mitigate the risk and impact of such disasters, according to a survey by IBGE, the national census and statistics bureau. An article published in the [...]

Brazilian researchers have developed a computer program that locates swimming pools and rooftop water tanks in aerial photographs with the aid of artificial intelligence to help identify areas vulnerable to infestation by Aedes aegypti, the mosquito that transmits dengue, zika, chikungunya and yellow fever. The innovation, which can also be used as a public policy tool for dynamic socio-economic mapping of urban areas, resulted from research and development work by professionals at the [...]

The study could serve to ensure that future generations are not affected by such diseases. Existing treatments are palliative, aimed at improving the quality of life for the patient or delaying the progression of the disease. A research article published in the journal Science Advances describes a mechanism that helps explain certain types of genetic disorders known as mitochondrial diseases that are transmitted from mother to child. The study it reports could serve the basis of novel [...]

Vaccination has changed the profile of hospitalized COVID-19 patients and people who die from the disease in Brazil. A study conducted in São José do Rio Preto, in the state of São Paulo, Brazil, reports on the start of this process. Researchers affiliated with the Virology Laboratory at São José do Rio Preto Medical School (FAMERP) retrospectively analyzed data for 2,777 patients treated between January 5 and September 12, 2021, at the region’s base [...]