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Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will be possible to seek more potent molecules capable of destroying the pathogens directly, with fewer adverse side-effects for patients. The study detailed the structural characteristics of the protein deoxyhypusine synthase (DHS), found in Brugia malayi, one of the [...]

Researchers based in Brazil and the United States have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals. The analysis revealed that the toxins that can act on the nervous system, cardiovascular system, and cell walls, among other functions, paving the way to the discovery of novel medications. “Tube anemones and sea [...]

A group of researchers at the University of São Paulo’s Engineering School (POLI-USP) in Brazil have developed a mechanical ventilator that costs only approximately 7% as much as a conventional ventilator. Called Inspire, it has an open patent allowing royalty-free manufacturing, although as a life support device, its distribution is controlled. A pilot batch will be produced by the Brazilian Navy for use in clinical trials. Twenty companies are interested in making the [...]

On April 8, 2020, São Paulo-based Magnamed signed an agreement with Brazil’s Health Ministry for the supply of 6,500 mechanical ventilators by August of this year. The agreement is designed to help meet growing demand for ventilators from hospitals across the country as they struggle to provide critical care for COVID-19 patients. To achieve this goal, Magnamed will partner with the following companies: Positivo, Brazil’s largest computer maker; Suzano, one of the [...]

In contrast with China and other countries where the disease spread slowly, in Brazil more than 300 people started the epidemic; most were passengers flying in from Italy Italy was the main origin of the individuals who first brought the novel coronavirus to Brazil, according to a study by Brazilian researchers in collaboration with colleagues in the United Kingdom, Canada and the United States. The COVID-19 pandemic arrived in Brazil between February and early March. “In contrast with [...]

In an article published in Scientific Reports, researchers affiliated with the University of São Paulo (USP) in Brazil describe experiments performed with mice that show how genetic factors can determine whether an individual is susceptible or resistant to leishmaniasis. According to the authors, the results will contribute to a better understanding of leishmaniasis in humans and help to clarify why only some of those individuals infected develop the disease. Leishmaniasis is caused by [...]