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A specific anthrax toxin can silence pain
Publicado em 29 de dezembro de 2021
Anthrax has a scary reputation. Widely known to cause serious lung infections in humans and unsightly, albeit painless, skin lesions in livestock and people, the anthrax bacterium has even been used as a weapon of terror.
Now the findings of a new study suggest the dreaded microbe also has unexpected beneficial potential — one of its toxins can silence multiple types of pain in animals.
The research reveals that this specific anthrax toxin works to alter signaling in pain-sensing [...]
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Torquetenovirus (TTV) load in people infected by SARS-CoV-2 can be used as a marker of COVID-19 severity and recovery
Publicado em 07 novembro 2021Torquetenovirus (TTV) is one of the viruses most frequently found in the human organism. It is also common in monkeys and domestic animals. Its presence has not been associated with any known disease, but its excessive replication is a sign that something is wrong with the immune system. The correlation between high TTV load and immunosuppression has been used in medicine in certain contexts, such as monitoring transplant patients who take medication to prevent rejection of the transplanted [...]ver notícia -
Irisin Produced During Exercising Can Prevent COVID-19 Disease Severity By Modulating Host Genes
Publicado em 01 setembro 2021A study conducted last year by Brazilian researchers from São Paulo State University (UNESP) is once again getting revived by various research groups and a few clinical trials are expected to start soon based on those earlier significant findings. The study team then had found that the hormone Irisin produced during exercising can prevent COVID-19 disease severity by modulating host genes. The study findings also illustrate why it is important for all during the COVID-19 pandemic to [...]ver notícia -
The drug ambrisentan significantly reduce the capacity of tumor cells to migrate and invade other tissues
Publicado em 17 dezembro 2020A drug used to treat pulmonary hypertension significantly reduced the capacity of tumor cells to migrate and invade other tissues in trials involving pancreatic, ovarian, breast cancer, and leukemia cell lines. Furthermore, in mice with an aggressive form of breast cancer, the drug reduced the incidence of metastasis in the liver and lungs by 47% and lengthened survival compared with untreated animals. The study is published in Scientific Reports. “The drug ambrisentan is an [...]ver notícia -
Vigorous physical exercise can reduce accumulated liver fat and in a short time span improve blood sugar control in obese and diabetic individuals
Publicado em 15 agosto 2019Research conducted at the University of Campinas (UNICAMP) in São Paulo State, Brazil, shows that vigorous physical exercise such as strength and weight training can reduce accumulated liver fat and improve blood sugar control in obese and diabetic individuals in a short time span, even before significant weight loss occurs. In experiments with mice, researchers at UNICAMP’s Molecular Biology of Exercise Laboratory (LaBMEx) found that two weeks of such exercise was [...]ver notícia -
Adolescents : skip breakfast it’s correlates directly with increased waist circumference and BMI
Publicado em 23 julho 2019A paper published in Scientific Reports describes how researchers affiliated with the University of São Paulo’s Medical School (FM-USP) in Brazil and colleagues at institutions in Europe evaluated behaviors leading to weight gain in adolescents. Childhoodobesitycan favor the premature emergence of health issues such as type 2 diabetes and cardiovascular disease. The main finding is that skipping breakfast, a common habit among teenagers, correlates directly with increased waist [...]ver notícia -
Curcumin can help prevent or combat stomach cancer
Publicado em 23 abril 2019Curcuminis widely used to impart color and flavor to food, but scientists have discovered that this yellow powder derived from the roots of the turmeric plant (Curcuma longa) can also help prevent or combat stomach cancer. The study by researchers at the Federal University of São Paulo (UNIFESP) and the Federal University of Pará (UFPA) in Brazil identified possible therapeutic effects of this pigment and of other bioactive compounds found in food on stomach cancer, the third and [...]ver notícia -
Study in six countries identifies groups that are vulnerable to severe mental illness
Publicado emYoung males, ethnic minorities and people living in socioeconomically disadvantaged areas are more likely to experience first-episode psychosis, defined as the first manifestation of one or more severe mental disorders including schizophrenia, bipolar affective disorder, and depression with psychotic symptoms such as hallucinations, delusions and cognitive disorganization. This is the main finding of a study conducted by an international consortium that estimated the incidence of first-episode [...]ver notícia