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Estudo conduzido no Instituto de Ciências Biomédicas da Universidade de São Paulo (ICB-USP) e divulgado na revista Frontiers in Immunology lança luz sobre a chamada síndrome pós-Covid —termo que abrange o conjunto de sintomas que permanecem ativos em alguns pacientes após a fase aguda da infecção pelo SARS-CoV-2. No trabalho, os pesquisadores analisaram os autoanticorpos (anticorpos que [...]

A dor neuropática é um tipo de dor crônica decorrente de lesão no sistema nervoso provocada, principalmente, por doenças metabólicas, como diabetes e artrite, ou por efeitos colaterais de alguns tipos de quimioterapia. Estima-se que afete entre 3% e 15% da população, dependendo do país, e não há medicamentos específicos para tratá-la —as drogas usadas atualmente foram [...]

Depression affects 10%-16% of pregnant women worldwide. Most get better with the help of antidepressant drugs. Although the safety of using antidepressants during pregnancy is endorsed by science, their effects on fetal neurodevelopment are poorly understood and should be studied with advanced techniques such as genomics. This is the main conclusion reached by a group of Brazilian researchers in a review of more than 100 scientific articles on fetal exposure to these drugs, especially [...]

An article published in Scientific Reports describes a study demonstrating the effectiveness of a peptide developed by Brazilian scientists, called Rb4, in combating cancer progression in an animal model, especially malignant melanoma. The molecule holds promise for the treatment of drug-resistant tumors.  Source | FAPESP

Based on data for 3,587 adolescents aged 12-19 who took part in the 2011-16 National Health and Nutrition Examination Survey (NHANES) in the United States, researchers at the University of São Paulo (USP) in Brazil have calculated the impact of consuming ultra-processed foods on the risk of obesity. They divided participants in the study into three groups according to the amount of ultra-processed foods consumed. When they compared those with the highest level (64% of total diet by [...]

A qualitative study conducted by researchers at the University of São Paulo's School of Arts, Sciences and Humanities (EACH-USP) in Brazil suggests that gender influences how people suffering from alcohol use disorder cope with their condition. The principal investigator was Professor Edemilson de Campos, who was supported by FAPESP and collaborated with Nadia Narchi, also a professor at EACH-USP. The results are reported in an article published in the journal Drug and Alcohol [...]

Cardiopulmonary exercise testing (CPET), also known as ergospirometry, can be used for early detection of respiratory disorders in overweight and obese individuals. This is the main finding of a study by Brazilian researchers who set out to assess the influence of obesity on the physiological responses obtained in CPET. The study showed that the main ventilatory responses were unaltered in obese volunteers. For example, the ratio of minute ventilation (VE, the volume of air exhaled in one [...]