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Torquetenovirus (TTV) is one of the viruses most frequently found in the human organism. It is also common in monkeys and domestic animals. Its presence has not been associated with any known disease, but its excessive replication is a sign that something is wrong with the immune system. The correlation between high TTV load and immunosuppression has been used in medicine in certain contexts, such as monitoring transplant patients who take medication to prevent rejection of the transplanted [...]

The anti-coagulant heparin reduces the likelihood of death from COVID-19 by 78% when administered in therapeutic doses to patients with signs of respiratory failure on admission to hospital, according to a study reported on October 14 in the British Medical Journal. The World Health Organization (WHO) currently recommends only prophylactic use of heparin for such patients. The prophylactic dose of the drug, prescribed mainly to prevent blood clots, is only a quarter of the therapeutic dose. [...]

The Roman Empire was ruled by 175 men, from Augustus (63 BCE-19 CE) to Constantine XI (1405-53), including the Eastern or Byzantine Empire after the split in 395 CE, but excluding those who did not rule in their own right because they were minors during regencies or co-emperors. Only 24.8% of the 69 rulers of the Western Empire died of natural causes. The rest died a violent death on the battlefield or in palace plots. Considering all 175, 30% were murdered, committed suicide or died in [...]

Repercussão de notícia produzida pela Agência FAPESP sobre pesquisa que mostra que o uso da curcumina, substância encontrada no açafrão-da-terra (Curcuma longa), aliada à terapia fotodinâmica foi eficaz na redução da carga parasitária e até na eliminação do protozoário Leishmania. O estudo aponta que aplicações de curcumina associadas à irradiação de LED azul, conseguiram inativar células do sistema imune (macrófagos) infectadas com Leishmania braziliensis, a espécie mais comum no país, e Leishmania major, sem afetar as células saudáveis. O resultado, descrito em artigo publicado na revista Antibiotics, aponta um caminho para futuras pesquisas em humanos buscando tratamentos mais eficazes e direcionados para a leishmaniose. Conduzido por pesquisadores da Universidade do Vale do Paraíba (Univap), em São José dos Campos, no âmbito do Centro de Pesquisa em Óptica e Fotônica, CePOF, um dos CEPIDs financiados pela FAPESP, o trabalho teve também apoio da Fundação por meio de Auxílio à Pesquisa - Regular

The calories that children and adolescents consumed from ultraprocessed foods jumped from 61% to 67% of total caloric intake from 1999 to 2018, according to a new study from researchers at the Friedman School of Nutrition Science & Policy at Tufts University. Published August 10, 2021, in JAMA, the study analyzed dietary intake from 33,795 children and adolescents nationwide. “Some whole grain breads and dairy foods are ultraprocessed, and they’re healthier [...]

Regular muscle strengthening exercises associated with aerobic activities can reduce cancer mortality, according to a systematic review of epidemiological studies. Workouts with squats, rowing, planks, weight training and so on can reduce the probability of dying from cancer by 14%. When these exercises are combined with aerobic activities, the benefit is even greater, potentially reducing mortality by 28%. “Physical activity has been associated with a reduced risk of several types of [...]

The COVID-19 pandemic and the situations of stress and sadness associated with it have not significantly increased the prevalence of depression and anxiety among participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil) who live in the city of São Paulo. ELSA-Brazil has been monitoring the overall health of 15,000 civil servants at six public universities and research centers in Brazil since 2008. The survey on mental health during the pandemic was conducted in [...]

In a study involving 34 women aged 50-70, researchers at the University of São Paulo (USP) in Brazil performed objective measurements of the impact on the subjects’ health of the decrease in physical activity observed during the period of social distancing and isolation imposed by COVID-19. Tests conducted after the first 16 weeks of confinement pointed to a deterioration in their overall health, including loss of muscle strength and diminished aerobic capacity, as well as elevated [...]

Fully occupied intensive care units (ICUs). Physically and mentally exhausted health workers. Chaotically overcrowded hospitals. These and similar problems posed by the COVID-19 pandemic in Brazil have created ideal conditions for the emergence of Candida auris, a microorganism some are calling a “superfungus” because of the speed with which it has developed drug resistance. The first two cases were confirmed in December 2020 at a hospital in Salvador (state of Bahia, Northeast [...]