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Chagas disease, which is caused by a protozoan parasite Trypanosoma cruzi It affects about 8 million people worldwide. More than a third of them have severe heart or digestive problems with an increased risk of death. The process that leads to this clinical condition is not fully understood. Article published in the journal Biomedicine He describes a study led by Brazilian researchers showing that mutations occurred in the mitochondrial genes of patients with Chagas disease, a disorder in [...]

Rapid, low-cost, and accurate tests are still required for epidemiological surveillance and healthcare services to monitor and contain the spread of SARS-CoV-2. Brazilian researchers have contributed to this field’s efforts by creating an electrochemical immunosensor that identifies antibodies against the virus. The innovation is described in an article published in the journal ACS Biomaterials Science and Engineering. In search of a novel diagnostic method, the group opted for a [...]

Summary: Researchers identify a neuromuscular circuit that links muscle fat burning during physical exercise to protein action in the brain. source: FAPESP Article published in science progress Describes the neuromuscular circuit that links muscle fat burning to protein action in the brain. The findings, obtained by researchers at the University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil, contribute to a deeper understanding of how regular physical [...]

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil indicate that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits the replication of SARS-CoV-2 as well as the exacerbated inflammatory response that leads to death. in many people. Patients with severe COVID-19. More research is needed to see if the effects described in an article published in science progress has been confirmed in patients with the [...]

Melanopsin (OPN4) is a light-sensitive protein found in skin and retinal cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 may also participate in the development and progression of melanoma, the most aggressive type of skin cancer. In experiments with animals and genetically modified cells in the Comparative Physiology of Pigmentation Laboratory at the Institute of Biosciences (IB-USP), the researchers showed that the disease progresses [...]