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São Paulo, Brazil – In a study with 49 participants, researchers at the State University of Campinas found that daily consumption of a dietary supplement containing 15 g of the substance for five weeks improved glucose metabolism even after meals. The skin or peel of the Jaboticaba berry (Plinia jaboticaba), a native of the Brazilian Atlantic Rainforest, is usually thrown away because of its astringency (due to an abundance of mouth-puckering tannins), yet it can be a [...]

São Paulo, Brazil – A technology originally designed for spraying crops with biological pest control products can be used in urban environments to reduce proliferation of insects that carry viruses harmful to humans, such as the mosquito Aedes aegypti, which transmits dengue, yellow fever, zika and chikungunya.   Developed by BirdView, a startup based in São Manuel (São Paulo state, Brazil), in collaboration with EMBRAPA Instrumentation – one of [...]

São Paulo, Brazil – A novel therapeutic strategy developed by researchers at São Paulo State University (UNESP) could revolutionize the treatment of visceral leishmaniasis, a neglected tropical disease (NTD) transmitted by sandflies. Some 12 million people suffer from the disease worldwide, and 700,000 to 1 million new cases of occur annually, according to the World Health Organization (WHO). The technique developed by the researchers involved the use of lipid [...]

São Paulo, Brazil – CD4 + T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections. However, an article published in the journal Cell Reports shows that an imbalance in the volumes of these defense cells in different parts of the lung in response to infection can do more harm than good. The study described in the article involved infecting mice with hypervirulent tuberculosis and influenza. The authors [...]

São Paulo, Brazil – A protein that has been widely studied owing to its association with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) is also linked to medulloblastoma, a type of central nervous system cancer. Medulloblastoma is one of the most common and aggressive brain tumors in children, arising from undifferentiated cells during early neural development. A study led by a group of Brazilian scientists has shown in vitro and in vivo that the gene [...]

São Paulo, Brazil – A single-dose dengue vaccine produced by Butantan Institute in São Paulo state (Brazil) prevents development of the disease in 79.6% of those vaccinated, according to an article published today in The New England Journal of Medicine. Called Butantan-DV, the vaccine contains attenuated versions of all four dengue virus serotypes. The results of the ongoing Phase 3 trial show that it is safe and effective for all age groups between 2 and 59, and for people [...]

São Paulo, Brazil – Analysis of occurrence and co-occurrence patterns shows the highest-risk clusters of chikungunya and zika in Brazil spreading from the Northeast to the Center-West and coastal areas of São Paulo state and Rio de Janeiro state in the Southeast between 2018 and 2021, and increasing again in the Northeast between 2019 and 2021. In Brazil overall, spatial variations in the temporal trends for chikungunya and zika decreased 13% and 40% respectively, but 85% [...]

São Paulo, Brazil – A 30-minute walk at moderate intensity temporarily reduced blood pressure in women with rheumatoid arthritis, not only at rest but also under stress. This was the conclusion drawn from a study involving physical and cognitive tests conducted at the University of São Paulo (USP) in Brazil. The study was reported in an article published in the Journal of Human Hypertension and was supported by FAPESP as part of a Thematic Project on the effects of [...]

The origin of the virus responsible for the ongoingyellow feverepidemic in Brazil, the worst for 40 years, has just been identified by scientists affiliated with two Brazilian institutions: Adolfo Lutz Institute (IAL) and the University of Sao Paulo (USP). By means of a molecular study ofyellow feverviruses found in dead monkeys and in mosquitoes, the group discovered that the strain behind the current epidemic originated in Pará State in North Brazil in 1980. The virus infected [...]