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Researchers at the University of Campinas (UNICAMP) in São Paulo state, Brazil, have resorted to a thoroughly unconventional method to treat COVID-19 in a patient with a rare genetic disease that makes her immune system unable to combat viruses and other pathogens. She was instructed to take 30 milliliters of breast milk every three hours for a week. The breast milk was donated by a woman who had been vaccinated against SARS-CoV-2. After testing positive for 120 days by RT-PCR, the [...]

A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers. According to an article published in the International Journal of Pharmaceutics the potential treatment was shown to be effective in isolated cells and animal models thanks to a combination of nanotechnology, chemotherapy and a monoclonal antibody. Glioblastoma multiforme accounts for 60% [...]

A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers. According to an articlepublishedin theInternational Journal of Pharmaceuticsthe potential treatment was shown to be effective in isolated cells and animal models thanks to a combination of nanotechnology, chemotherapy and a monoclonal antibody. A drug carrier able to reach the brain, bind [...]

Converting agroindustrial waste into molecules of interest to society, such as biofuels and biochemicals, is one of the ways to mitigate dependence on oil and other fossil fuels. As one of the world’s largest producers of plant biomass, Brazil is well-placed to lead this transition, but lignocellulosic raw materials (containing lignin, hemicellulose and cellulose) are hard to deconstruct, or (more technically put) recalcitrant to microbial and enzymatic degradation . Converting [...]

Vaccines can be made over 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to a study by an international collaboration in which Brazilian researchers took part. An article reporting the results is published in Nature. Vaccines can be made over 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to a study by an international collaboration in which Brazilian researchers took part. An article [...]

Brazilian researchers have analyzed the mechanisms by which estuarine plants absorb iron, and used their findings to recommend a promising phytoremediation technique for the rehabilitation of water and soil contaminated by environmental disasters such as the 2015 collapse of the Fundão iron mine tailings dam in Mariana, Minas Gerais state (Southeast Brazil). An article on the study is published in the Journal of Hazardous Materials. The researchers conclude [...]

A study conducted at São Paulo State University (UNESP) in Brazil shows that even mild to moderate infection by SARS-CoV-2 can cause an imbalance in the cardiovascular system of young adults without pre-existing diseases. The researchers also concluded that both obesity and a low level of physical activity are key factors in post-COVID that help alter the autonomic nervous system, which regulates such vital functions as blood pressure, heart rate and breathing. The study, which was [...]

Brazilian researchers have developed a computer program that locates swimming pools and rooftop water tanks in aerial photographs with the aid of artificial intelligence to help identify areas vulnerable to infestation by Aedes aegyptithe mosquito that transmits dengue, zika, chikungunya and yellow fever. The innovation, which can also be used as a public policy tool for dynamic socio-economic mapping of urban areas, resulted from research and development work by professionals at the [...]

The study could serve to ensure that future generations are not affected by such diseases. Existing treatments are palliative, aimed at improving the quality of life for the patient or delaying the progression of the disease. A research article published in the journal Science Advances describes a mechanism that helps explain certain types of genetic disorders known as mitochondrial diseases that are transmitted from mother to child. The study it reports could serve the basis of novel [...]