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Un grupo de científicos encabezado por investigadores de la Universidad de São Paulo (USP) con sede en la localidad de São Carlos, en Brasil, identificó una serie de compuestos bioactivos en una especie de esponja marina recolectada en Fernando de Noronha, un archipiélago situado a unos 400 kilómetros de la costa nordeste del país. Algunas de esas sustancias mostraron capacidad para eliminar bacterias resistentes a los antibióticos [...]

Eine Forschergruppe unter der Leitung von Wissenschaftlern der Universität von São Paulo (USP) in São Carlos, Brasilien, hat in einem Meeresschwamm, der auf Fernando de Noronha, einer Inselgruppe etwa 400 km vor der Küste der nordöstlichen Region Brasiliens, gesammelt wurde, eine Reihe bioaktiver Verbindungen identifiziert. Einige der Substanzen erwiesen sich als fähig, Bakterien abzutöten, die gegen die derzeit verfügbaren Antibiotika resistent sind, [...]

Un groupe de recherche dirigé par des scientifiques de l'Université de São Paulo (USP) à São Carlos, au Brésil, a identifié un certain nombre de composés bioactifs dans une éponge marine recueillie sur Fernando de Noronha, un archipel situé à environ 400 km au large des côtes de la région Nord-Est du Brésil. Certaines de ces substances se sont révélées capables de tuer des [...]

A study conducted at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines. However, while in vitro treatment of cells with these molecules did not significantly influence local tissue infection, it reduced [...]

Two independent clinical studies – one by researchers at the Center for Cell-Based Therapy (CTC) in Ribeirão Preto, state of São Paulo (Brazil), on the monoclonal antibody eculizumab, and the other by scientists at the University of Pennsylvania in Philadelphia (USA) on an experimental drug called AMY-101 – observed a significant anti-inflammatory effect that contributed to a faster recovery by severe COVID-19 patients. The results of the two studies, which set out to [...]

The enzyme discovered by the group enables the release of carbohydrates resulting from saccharification and their fermentation by yeast to occur at the same time. Second-generation ethanol (also called cellulosic ethanol) open perspectives for optimizing alcohol production. Since 2G ethanol is obtained from from sugarcane straw and bagasse, it basically makes it possible converting waste into energy. Holder of the world's best biomass and boasting the installed industrial capacity, the [...]

The search for vaccines, treatments and preventive methods against infection by emerging viruses is one of the major challenges of global epidemiology. New pathological agents continue to emerge, such as the arbovirus transmitted by insects (in this case mosquitoes) that causes West Nile fever, named after being identified in Egypt, during the 1950s. The disease affects thousands of people each year and is asymptomatic in 80% of cases. Roughly one in five infected people develops fever and [...]

Scheme Lab, a biotech startup incubated at the Center for Innovation, Entrepreneurship & Technology (CIETEC), in São Paulo, Brazil, is developing genetic tests that can be used anywhere - in factories, on farms, or even at home - without the need for analysis by specialized laboratories. These "point-of-care" tests will identify genetic alterations that can be used to measure meat quality, the characteristics of seedlings and plants, or the resistance of disease-transmitting mosquitoes, [...]

Researchers affiliated with the University of Campinas (UNICAMP) in São Paulo State, Brazil, have shown that genetic information can be used to improve early prediction of the response to drugs in patients with mesial temporal lobe epilepsy (MTLE), one of the most severe forms of epilepsy. Patients who do not respond well to treatment with antiepileptic drugs are candidates for surgery. The research was conducted at the Brazilian Research Institute for Neuroscience and Neurotechnology [...]