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Publicado em 18 de abril de 2022

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Vaccines can be made over 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to a study by an international collaboration in which Brazilian researchers took part. An article reporting the results is published in Nature.Three research groups collaborated on the study, one affiliated with the University of Michigan in the United States, and another with Jiangnan University in China. The Brazilian group was led by André Farias de Moura, a professor in the Chemistry Department at the Federal University of São Carlos (UFSCar) and a researcher with the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) funded by FAPESP.The study did not involve COVID-19 vaccines because it began well before the pandemic. The researchers used vaccines developed to combat a specific influenza virus strain. While this is not the strain that is currently circulating in Brazil, in principle the results can be generalized for any type of vaccine, evidently with case-by-case complementary studies. The reason is that left-handed chiral gold nanoparticles are not the active ingredient, but an adjuvant that potentiates the recipient's immune response."The key to understanding the contribution of these nanoparticles is the concept of chirality, which applies to an object or system that can't be superimposed on its own mirror image," Moura told Agência FAPESP.

Fonte: https://www.futuretimeline.net/forum/viewtopic.php?f=17&p=18576