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In recent weeks, you may have noticed some familiar headlines about red wine and cardiovascular health. Why the sudden return of these stories? Because of an article recently published in the American Journal of Clinical Nutrition. Funded in part by a grant from the São Paulo Research Foundation (FAPESP), the “Wine Flora Study” was carried out by prominent researchers from institutions in South America, Europe, and the United States: University of São Paulo, Brazil; [...]

Research led by scientists at the University of São Paulo (USP) in Brazil has found that the coronavirus that causes COVID-19 can be detected in tears collected by swabbing. A swab is an absorbent cotton pad on a flexible rod used to clean wounds, apply medication and take specimens. The researchers analyzed samples from patients diagnosed with the disease by conventional methods and admitted to the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC) run by the Bauru Dental [...]

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate. In laboratory tests, the researchers inhibited interaction between the molecules using a drug and thereby reduced viral [...]

In an article published in the journal eLife, researchers at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, describe a novel strategy for detecting imbalances and complications in patients infected by Plasmodium vivax, one of the parasites that causes malaria and the main cause of the disease in the Americas. According to the study, total parasite biomass in the patient is a better predictor of the extent of infection outside the bloodstream than parasitemia, [...]

Recipients of liver transplants who contracted COVID-19 recovered faster with less severe inflammation than heart or kidney transplant recipients, and some even did better than non-transplant patients, according to a study conducted at Hospital das Clínicas (HC), the hospital complex run by the University of São Paulo’s Medical School (FM-USP) in Brazil. An article describing the study and its main results is published in the journal Transplantology. The researchers [...]

A study published this May in the journal Clinical Infectious Diseases suggests that people who have had dengue in the past are twice as likely to develop symptoms of COVID-19 if they are infected by the novel coronavirus. The findings of the study were based on an analysis of blood samples from 1,285 inhabitants of Mâncio Lima, a small town in the state of Acre, part of Brazil's Amazon region. The principal investigator was Marcelo Urbano Ferreira, a professor at the University of [...]

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma. The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a popular aquarium species native to South Asia that shares 70% of its genome with humans and is widely used as [...]

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population. This difference has been confirmed by a method involving a panel of four biomarkers that distinguish benign from malignant thyroid cancer cases on the basis of gene expression. The tests were developed by researchers at the Federal [...]