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Both aging and obesity can impair the production of regulatory microRNAs by adipose tissue increasing the risk of developing conditions such as diabetes and dyslipidaemia however, researchers from the University of Campinas's Institute of Biology (IB-UNICAMP) in the state of São Paulo, Brazil, have reported that this degenerative process can be reversed by practicing regular aerobic exercise. Their findings, ‘Dynamic changes in DICER levels in adipose tissue control metabolic [...]

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals. Scientists also suspect that during infection, fat cells release substances into the bloodstream that boost the inflammatory reaction triggered by the virus in the organism. These hypotheses are being investigated by researchers at the [...]

Researchers at the University of Campinas (UNICAMP) in São Paulo State, Brazil, have developed a computer program that analyses molecules in blood plasma to search for biomarkers that identify individuals who are at risk of becoming overweight and developing obesity-related diseases. The project was conducted in Brazil with funding from Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) . The results are described in the paper, ‘Combining [...]

Saliva can be used for the early detection of the risk of developing diseases associated with surplus body fat, according to researchers at the Federal University of São Paulo (UNIFESP) and the University of Campinas (UNICAMP) in Brazil, who performed a study in which they used the level of uric acid in saliva to predict body fat percentages in teenagers and identify those with surplus fat even if they had no symptoms of chronic obesity-related disease. The goal of the study was to [...]

Researchers at the University of São Paulo (USP) in Brazil assessing transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique that can help reduce appetite, food intake and body weight but only in some subjects, have reported that a patient's genetic profile appears to be a key factor in determining the outcome.  The paper, ‘Appetite effects of prefrontal stimulation depend on COMT Val158Met polymorphism: A randomized clinical trial’, [...]