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The discovery of a possible “Achilles heel” in Nev, the protein essential to HIV and its ability to cause AIDS, paves the way for the development of a new class of drugs against the virus. Researchers have succeeded in showing a structure that binds this protein to another called AP-2 and regulates endocytosis, which is the process by which cells take in substances such as nutrients or pathogens by immersing them in a vesicle. As a result, it is becoming increasingly clear how Nef [...]