Asthma It is one of the major noncommunicable diseases (NCDs) affecting children and adults worldwide.
In accordance with World Health Organization (WHO), it is calculated that in 2019, asthma affected 262 million people and called 461 thousand deaths.
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Most of the deaths associated with asthma, occur in low and middle income countries Where no diagnosis And care According to the WHO, this is a recurring problem.
Asthma can be controlled with medication, but now it can be cured thanks to a new discovery in Brazil.
Frogfish venom effective in treating asthma
researchers Institute of Butantan in Brazil identified a substance isolated from the poison of some fish With anti-inflammatory properties it was shown effective in the treatment of asthma.
The institution said that the protein was able to reduce the number of cells by more than 75% which are due to asthma cause inflammation and damage to lung tissue.
The study treated asthma with TnP Protein, derived from the venom of the palefin frogfish (“Thalassophryne nattereri”), commonly known as Nobody in Brazil.
Characteristics of frogfish or nikima
Nikim whose poison studied by the Institute of Butantan since 1996, This poisonous fish that lives on the coast of the Atlantic Ocean between northeast Brazil and northwest Colombia and that, hiding in holes in the sand and survive up to 18 hours without water, This often causes accidents among bathers.
To connect with its thorns inflict sharp pain, feeling burn, edema and tissue necrosis.
Findings from the Asthma Poisoning Study
In a specific case of asthma experts conducted tests on a group of animals with asthma particle treated, with the other group received dexamethasone, what drug is used to fight the disease, and with t The third group received a placebo.
In animals treated with TnP, in addition to a 75% reduction in the number of cells that cause swelling and damage to lung tissues, the substance reduced by 100% the number of eosinophils responsible for inflammation in half of asthma patients.
The synthesized protein treatment also reduced the hyperplasia of mucus-producing cells in the bronchi, which doctors say is important in relieving asthma symptoms.
Unlike traditional asthma treatments, which can cause symptoms such as heart palpitations, agitation, and headache, TnP had no side effects.