The new coronavirus is capable of infecting cells tissue cerebral and can cause “significant alterations” in the region of the cortex even in patients mild, as reported this Wednesday, October 14, 2020 by academic sources based on a study.
The research, conducted by 74 scientists from various institutions brazilian, including the University of Campinas (Unicamp) and the college of Sao Paulo (USP), details the effects of SARS-CoV-2 in the brain, especially in astrocytes.
“We show for the first time that (the coronavirus) does indeed infect and replicate in astrocitos and that this may decrease the viability of neurons “, explained Daniel Martins-de-Souza, one of the coordinators of the study, financed by the Foundation for Amparo to Research of the State of Sao Paulo (FAPESP).
The researcher noted that there were “large Doubts “on whether the brain dysfunction registered in some patients with covid-19 was as a result of a “ inflammation systemic “or if really the coronavirus harmed directly the operation of the nerve cells or infects them.
“Our results indicate that SARS-CoV-2 can enter the brain cells Y to affect his functioning “, full.
The astrocitos Are the cells most abundant of the Central Nervous System and perform multiple functions, including providing sustenance and nutrients at neurons, regulate the concentration of neurotransmitters and help to protect al brain of pathogens and toxins.
The scientists detected the infection of this type of cells from analyzes carried out in the brain tissues of 26 patients what they died by the covid-19.
The presence of coronavirus was confirmed at 26 samples studied and five of them also recorded “ alterations suggesting a possible damage al nervous system central “.
“We observe in these five cases signs of necrosis e inflammation, as edema The neuronal injuries of another rank “, indicated Thiago Cunha, professor of the USP and who did not rule out similar damages in the other 21 patients deceased, but in different regions of the brain tissue.
On the other hand, the researchers also studied 81 patients who contracted covid-19, but only developed mild symptoms and they didn’t have the need to be hospitalized.
The analyzes occurred 60 days after the date of diagnosis and revealed that a third of the participants still had neurological symptoms The neuropsiquiátricos.
The main complaints were dolores of head (40%), fatigue (40%), disturbance in the memory (30%), anxiety (28%), loss of smell (28%), drowsiness daytime (25%), depression (20%), loss of gusto (16%) and libido (14%).
Furthermore, from the results of MRIs, it was possible to perceive that some regions of the cortex of volunteers had a thickness lower than the average, and others, on the contrary, presented a increase of size, which, according to the researchers, may indicate some degree of edema.
“We observe atrophy in areas related, for example, to anxiety, one of the symptoms more frequent in the group studied. Considering that the prevalence half of disorders of anxiety in the Brazilian population is 9%, the 28% we find is a high number Y alarming “said Professor Clarissa Yasuda, from the Institute for Research on Neuroscience and Neurotechnology.
“The question that remains now is whether those symptoms will be passengers The permanent “He added to later inform that they will continue accompanying the volunteers in order to answer that question.
Brazil is the second country with the most deaths related to the new coronavirus (151 747), behind United States, and the third with more Confirmed cases disease (5,140,863), after the USA and India.